Practical Implementation of Lipid Lowering for Cardiovascular Risk Reduction in Primary Care

Authors

  • G.B. John Mancini, MD, FRCPC, FACC Cardiovascular Imaging Research Core Laboratoryl CardioRisk Clinic, Vancouver General Hospital; Centre for Cardiovascular Innovation; Division of Cardiology, University of British Columbia, Vancouver, BC

DOI:

https://doi.org/10.58931/cpct.2023.1319

Abstract

With the advent of safe lipid-lowering drugs, particularly statins and non-statin agents such as ezetimibe, and with the emergence of newer therapeutics such as monoclonal antibodies and RNA technologies, it has become apparent that major adverse cardiovascular (CV) events can be reduced both in primary and secondary prevention by 20–50% through lowering of low-density lipoprotein cholesterol (LDL-C) by 1–2 mmol/L. The purpose of this paper is to provide a pragmatic approach to the implementation of the 2021 Canadian Cardiovascular Society Guideline for managing dyslipidemia in adults.

Author Biography

G.B. John Mancini, MD, FRCPC, FACC, Cardiovascular Imaging Research Core Laboratoryl CardioRisk Clinic, Vancouver General Hospital; Centre for Cardiovascular Innovation; Division of Cardiology, University of British Columbia, Vancouver, BC

Dr. John Mancini was Chair of Medicine at the University of British Columbia from 1992 to 2002. He founded the CardioRisk Clinic at Vancouver Hospital and directs an imaging-based research program. The focus of the CardioRisk Clinic is to foster innovation in novel cardiovascular risk detection and provision of comprehensive primary and secondary cardiovascular preventive therapies. He has been a primary author of several guideline publications, including, most recently, the Canadian Cardiovascular Society Guidelines for Managing Dyslipidemia. (https://www.circl.ubc.ca)

References

Pearson GJ, Thanassoulis G, Anderson TJ, Barry AR, Couture P, Dayan N, Francis GA, Genest J, Grégoire J, Grover SA, Gupta M. 2021 Canadian Cardiovascular Society guidelines for the management of dyslipidemia for the prevention of cardiovascular disease in adults. Canadian Journal of Cardiology. 2021 Aug 1;37(8):1129-50. DOI: https://doi.org/10.1016/j.cjca.2021.03.016. DOI: https://doi.org/10.1016/j.cjca.2021.03.016

Published

2023-10-25

How to Cite

1.
Mancini GJ. Practical Implementation of Lipid Lowering for Cardiovascular Risk Reduction in Primary Care. Can Prim Care Today [Internet]. 2023 Oct. 25 [cited 2024 Jun. 18];1(3):9-15. Available from: https://canadianprimarycaretoday.com/article/view/1-3-mancini

Issue

Section

Articles